1. Prasad B. “Trio Whole Genome Sequencing in Patients of Loin Pain Hematuria Syndrome with Positive Family History”(2025). University of Saskatchewan, College of Medicine Research Awards (CoMRAD): $20,000
Comment: This study investigates shared genetic variants in familial LPHS using trio whole genome sequencing. It focuses on identifying intronic and exonic variants in non-collagenous basement membrane, endothelial, and podocyte proteins. The goal is to better understand molecular mechanisms underlying hematuria and pain in LPHS.
Contribution: 100%
Primary Investigator: Bhanu Prasad

2. Prasad B. “Decoding the ultra-rare disease – Loin Pain Hematuria Syndrome”. (2022) College of Medicine Research Awards (CoMRAD): $29.999.96.
Comment: This genomic study aims to identify the underlying genetic basis of LPHS. Despite multiple proposed mechanisms, the precise etiology remains unknown. This landmark study seeks to define molecular pathways driving LPHS pathophysiology.
Contribution: 100%
Primary Investigator: Bhanu Prasad

3. Prasad B. “Unravelling the cellular and molecular mechanisms of loin pain hematuria syndrome”, (2021) Otsuka Pharmaceuticals Canada Inc.: $30,000.
Comment: This study explores RNA, proteomic, and metabolomic profiles to understand LPHS at the molecular level. By examining downstream molecular domains, it aims to identify mechanisms responsible for hematuria and pain. This represents one of the first comprehensive molecular investigations in LPHS.
Contribution: 100%
Primary Investigator: Bhanu Prasad

4. Prasad B. “Feasibility Study of a Randomized Controlled Trial Investigating Renal Denervation as a Possible Treatment Option in Patients with Loin Pain Hematuria Syndrome” (2020). Hospitals of Regina Foundation: $68,000.
Comment: This is a single-centre feasibility study of a Randomized controlled trial with 10 patients to evaluate the efficacy of endovascular ablation of renal nerves vs. a sham procedure in patients with Loin Pain Hematuria Syndrome (LPHS). I conceived the study, wrote the initial draft, and contributed significantly to the final version.
Contribution: 100%
Primary Investigator: Bhanu Prasad

5. Prasad B. “Unraveling Cellular and Molecular Mechanism of LPHS to Understand Underlying Pathophysiology in Search for Prognostic Markers and Therapeutic Targets” (2020). Hospitals of Regina Foundation: $25,000.
Comment: This project compares gene signatures of LPHS patients with isolated hematuria cases to identify distinguishing molecular patterns. Proteomic analysis of kidney biopsies aims to better understand GBM organization. The study seeks prognostic markers and therapeutic targets.
Contribution: (100%).
Primary Investigator: Bhanu Prasad

6. Babu M, Siqueira WL, Falzarano D, Golshani A, Houry W. Kobasa D, Prasad B, Yang J. “Development of SARS-CoV-2 Peptide Therapeutics and Point-of-Care Salivary Diagnostics for Rapid Viral Detection” (2020). Canadian Institutes of Health Research (CIHR), COVID-19 Rapid Research Funding Call: $937,950.
Comment: This CIHR-funded study mapped interactions between SARS-CoV-2 proteins and human host factors using mass spectrometry. It aimed to identify antiviral targets and salivary biomarkers for rapid detection. The project supported therapeutic and diagnostic development during COVID-19.
Contribution: 10-15%
Co-Applicant: Bhanu Prasad

7. Prasad B, Jafari M, Tondon K, Goyal K, Garcia F, Berry W, Bancescu B. “Feasibility Study of a Randomized Controlled Trial Investigating Renal Denervation as a Possible Treatment Option in Patients with Loin Pain Hematuria Syndrome” (2019). Saskatchewan Health Research Foundation (SHRF), 2019 Collaborative Innovation Development Grant: $49,486.
Comment: This is a single centre feasibility study of a Randomized controlled trial with 10 patients to evaluate the efficacy of endovascular ablation of renal nerves vs. sham procedure in patients with Loin Pain Hematuria Syndrome (LPHS). I conceived the study, wrote the initial draft and contributed significantly to the final version.
Contribution: 75%
Primary Investigator: Bhanu Prasad

8. Prasad B, Holden R, Korkola, Goyal K, Tsui C. “Histological Burden of Calcification in Left Internal Mammary Artery Conduit Graft in Patients with Stage 5 chronic kidney disease” (2019). University of Saskatchewan, College of Medicine Research Award (CoMRAD): $20,314.85.
Comment: The primary objective of this study is to quantify the histological extent of vessel wall calcification in LIMA in stage 5 CKD patients undergoing coronary artery bypass graft (CABG). In this study, we would also like to histologically assess arterial calcification in non-CKD patients undergoing CABG and compare it to stage 5 CKD patients undergoing CABG.
Contribution: 80%.
Primary Investigator: Bhanu Prasad.

9. Goyal P, Prasad B, Garcia F, Omisore I. “Feasibility Study of a Randomized Controlled Trial Investigating Renal Denervation as a Possible Treatment Option in Patients with Loin Pain Hematuria Syndrome” (2019). University of Saskatchewan, 2019 College of Medicine Research Award (CoMRAD): $28,250.
Comment: This is a single-centre feasibility study of a Randomized controlled trial with 10 patients to evaluate the efficacy of endovascular ablation of renal nerves vs. sham procedure in patients with Loin Pain Hematuria Syndrome (LPHS). I conceived the study, wrote the initial draft and contributed significantly to the final version.
Contribution: 75%
Co-Investigator: Bhanu Prasad

10. Prasad B “Identifying Barriers to Home Therapies in Saskatchewan” (2019) Baxter Inc: $35,000.
Comment: Home therapies are underutilized in Canada in comparison to in-centre hemodialysis in Canada, including Saskatchewan. The primary objective of this study was to identify and assess patient-perceived barriers to peritoneal dialysis (PD) implementation in Saskatchewan. The secondary objectives were to examine variations in patient-perceived barriers to PD by dialysis units (main dialysis units vs satellite dialysis units) and specific challenges faced by First Nation patients residing on reserves.
Contribution: 80%
Primary Investigator: Bhanu Prasad.

11. Tennankore K, Gunaratnam L, Keough-Ryan T, Kiberd B, Prasad B, Rockwood K, Sills L, Suri R, Tangri N, Vinson A, West K, Yohanna S, Doucette S, Gogan N, Koto P. “Frailty and the Kidney Transplant Wait List”. Canadian Institutes of Health Research (CIHR), Fall 2018 and Spring 2019 Project Grant: $321,300 over 5 years.
Comment: A multicenter CIHR-funded study comparing three frailty assessment tools in transplant candidates. It evaluated frailty’s role in waitlist outcomes and vulnerability. The study informs transplant risk stratification strategies.
Contribution: 15%.
Co-Applicant: Bhanu Prasad

12. Tangri N, Bohm C, Prasad B, Shah N, Duhamel T. “Frailty Predicts Early Death or Functional Decline after Dialysis in Patients with Chronic Kidney Disease” (2018). Canadian Frailty Network, Catalyst Grant Competition. $100,000 over 16 months.
Comment: Chronic kidney disease (CKD) is associated with declining physical function and activity. In the general population, lower physical activity is associated with poorer quality of life and greater all-cause mortality. This study aimed to assess whether lower physical activity levels are associated with adverse health outcomes in patients with advanced CKD.
Contribution: 20%.
Co-Investigator: Bhanu Prasad

13. Prasad B, Tangri N, St. Onge J, Blair T, Kozakewycz D, Kappel J. “Predicting Risk of Disease Progression in Patients with Chronic Kidney Disease in Saskatchewan” (2016). Collaborative Innovation Development Grant: $43,076 over 2 years.
Comment: A retrospective cohort study validating the Kidney Failure Risk Equation in Saskatchewan CKD patients. It analyzed healthcare utilization and costs across risk tertiles. The study supports risk-based resource allocation.
Contribution: 70%.
Primary Investigator: Bhanu Prasad.

14. Prasad B. “Incidence and Prevalence of Glomerulonephritis in Saskatchewan Based on Geographical Factors” (2016). Hospitals of Regina Foundation: $25,000.
Comment: The inflammation involving the filtering area of the kidney is called glomerulonephritis (GN). In this study, we plan to identify all subtypes of GN and associate it with geographical factors such as mines, refineries and coal plants. This study will be done in collaboration with the Health Quality Council (HQC)
Contribution: 100%
Primary Investigator: Bhanu Prasad.

15. Tangri N, Nishi C, Prasad B, Bohm C, Storsley L, Sathianathan C. “Frailty Affects Treatment Decisions and Outcomes in Chronic Kidney Disease” (2014). Kidney Foundation of Canada, Biomedical Research Grant: $97,520 over 3 years.
Comment: This is a prospective, multicenter, cohort study involving 600 patients with advanced CKD. Our objective was to determine the agreement between different frailty measures and physical function and their association with dialysis modality choice (home based versus in-center) and all-cause mortality in patients with advanced CKD.
Contribution: 20%.
Collaborator: Bhanu Prasad.

16. Prasad B. “Frailty and Outcomes in Renal Disease” (2013). Hospitals of Regina Foundation: $ 30,000
Comment: This is a prospective, multicenter, cohort study involving 600 patients with advanced CKD. Our objective was to determine the agreement between different frailty measures and physical function and their association with dialysis modality choice (home based versus in-center) and all-cause mortality in patients with advanced CKD.
Contribution: 100%
Co-Investigator: Bhanu Prasad.

17. Prasad B. “Prairie Renal Denervation Project” (2012). Medtronic External Research Program Grant: $100,000 USD over 5 years.
Comment: A pre-post intervention study to examine the effects of renal denervation on central blood pressures compared to peripheral blood pressures in patients with chronic kidney disease and resistant hypertension. This study was different as it looked at central pressures, pulse wave velocities in patients with advanced CKD.
Contribution: 100%
Primary Investigator: Bhanu Prasad.